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Genetic architecture of brain age and its causal relations with brain and mental disorders

10 May 2023

Abstract excerpt

Abstract The difference between chronological age and the apparent age of the brain estimated from brain imaging data—the brain age gap (BAG)—is widely considered a general indicator of brain health. Converging evidence supports that BAG is sensitive to an array of genetic and nongenetic traits and diseases, yet few studies have examined the genetic architecture and its corresponding causal relationships with...

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PMID: 37165155
DOI: 10.1038/s41380-023-02087-y

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