Article

Inhibition of Metabotropic Glutamate Receptor III facilitates sensitization to alkylating chemotherapeutics in Glioblastoma

2021-06-02

Abstract excerpt

<title>Abstract</title> <p>Glioblastoma (GBM), the most malignant tumor of the central nervous system, is marked by its dynamic response to microenvironmental niches. In particular, this cellular plasticity contributes to the development of an immediate resistance during tumor treatment. Novel insights into the developmental trajectory exhibited by GBM show a strong capability to respond to its microenvironment b...

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Literature Corpus work: 53205791-ed25-568d-b4ae-92623ba6963f
DOI: 10.21203/rs.3.rs-337223/v1

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