Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

NMDA Receptor-Mediated Signaling Pathways Enhance Radiation Resistance, Survival and Migration in Glioblastoma Cells—A Potential Target for Adjuvant Radiotherapy

9 Apr 2019

Abstract excerpt

Glioblastoma is one of the most aggressive malignant brain tumors, with a survival time less than 15 months and characterized by a high radioresistance and the property of infiltrating the brain. Recent data indicate that the malignancy of glioblastomas depends on glutamatergic signaling via ionotropic glutamate receptors. In this study we revealed functional expression of Ca2+-permeable NMDARs in three...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Glioma Diagnosis and Treatment
Share to MicroRNA in disease regulation
Share to Neuroscience and Neuropharmacology Research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 30970642
DOI: 10.3390/cancers11040503

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

NMDA Receptor-Mediated Signaling Pathways Enhance Radiation Resistance, Survival and Migration in Glioblastoma Cells—A Potential Target for Adjuvant RadiotherapyPMID 30970642Read ↗

Inhibition of Metabotropic Glutamate Receptor III facilitates sensitization to alkylating chemotherapeutics in GlioblastomaSemantic proximity Read ↗

Glutamate Receptors and Glioblastoma Multiforme: An Old “Route” for New PerspectivesSemantic proximity Read ↗

Involvement of CD73 and A2B Receptor in Radiation-Induced DNA Damage Response and Cell Migration in Human Glioblastoma A172 CellsSemantic proximity Read ↗

Molecular mechanisms of necrosis in glioblastoma: The role of glutamate excitotoxicitySemantic proximity Read ↗

Ca2+-Activated IK K+ Channel Blockade Radiosensitizes Glioblastoma CellsSemantic proximity Read ↗

Phenotypic Screening Identifies Flunarizine as an Inhibitor of Radiotherapy-Induced Astrocyte Reactivity with Therapeutic Potential in GlioblastomaSemantic proximity Read ↗

Role of phosphorylated Y1252, Y1336 and Y1472 on NR2B subunits in hypoxia tolerance of neuronal cell in vitro.Semantic proximity Read ↗

Metabotropic glutamate receptor-1: a potential therapeutic target for the treatment of breast cancer.Semantic proximity Read ↗

Cross Interaction between M2 Muscarinic Receptor and Notch1/EGFR Pathway in Human Glioblastoma Cancer Stem Cells: Effects on Cell Cycle Progression and SurvivalSemantic proximity Read ↗

Metabotropic Glutamate Receptor-1 as a Novel Target for the Antiangiogenic Treatment of Breast CancerSemantic proximity Read ↗

Genomics and transcriptomic alterations of the glutamate receptors in acute myeloid leukemia.Semantic proximity Read ↗

Silencing of selected glutamate receptor subunits modulates cancer growth.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.