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Article

Molecular mechanisms of necrosis in glioblastoma: The role of glutamate excitotoxicity

1 Oct 2009

Abstract excerpt

Glioblastomas continue to rank among the most lethal primary human tumors. Despite treatment with the most rigorous surgical interventions along with the most optimal chemotherapeutic and radiation regimens, the median survival is just 12-15 mo for patients with glioblastoma. Among the histological hallmarks of glioblastoma, necrosis has been demonstrated to be a powerful predictor of poor patient prognosis. Over...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 19770591
DOI: 10.4161/cbt.8.19.9762

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