Article

Genetic requirements for uropathogenic <i>E. coli</i> proliferation in the bladder cell infection cycle

2023-12-06

Abstract excerpt

<h4>ABSTRACT</h4> Uropathogenic Escherichia coli (UPEC) requires an adaptable physiology to survive the wide range of environments experienced in the host, including gut and urinary tract surfaces. To identify UPEC genes required during intracellular infection, we developed a transposon-directed insertion-site sequencing (TraDIS) approach for cellular infection models and searched for genes in a library of ∼20,0...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 369e9d54-aaad-5e3c-8c8d-4aa77877eb6e
DOI: 10.1101/2023.12.05.570251

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Genetic requirements for uropathogenic <i>E. coli</i> proliferation in the bladder cell infection cycleDOI 10.1101/2023.12.05.570251Read

Genetic requirements for uropathogenic E. coli proliferation in the bladder cell infection cycleSemantic proximity Read

Mapping Niche-specific Two-Component System Requirements in Uropathogenic <i>Escherichia coli</i>Semantic proximity Read

The <i>lac</i> operon in uropathogenic <i>Escherichia coli</i> enhances intracellular growth by enabling host glycan utilizationSemantic proximity Read

Maturation of Intracellular <i>Escherichia coli</i> Communities Requires SurASemantic proximity Read

Genome-Wide Discovery of Genes Required for Capsule Production by Uropathogenic Escherichia coliSemantic proximity Read

Intracellular Lifestyles and Immune Evasion Strategies of Uropathogenic<i>Escherichia coli</i>Semantic proximity Read

Type 1 fimbriae and extracellular polysaccharides are preeminent uropathogenic <i>Escherichia coli</i> virulence determinants in the murine urinary tractSemantic proximity Read

Transposon Mutagenesis Identifies Uropathogenic Escherichia coli Biofilm FactorsSemantic proximity Read

Functional and genetic adaptations contributing to <i>Enterococcus faecalis</i> persistence in the female urinary tractSemantic proximity Read

Glycosuria alters uropathogenic <i>Escherichia coli</i> global gene expression and virulenceSemantic proximity Read

Transposon mutagenesis screen in <i>Klebsiella pneumoniae</i> identifies genetic determinants required for growth in human urine and serumSemantic proximity Read

Conditionally essential genes for survival during starvation in <i>Enterococcus faecium</i> E745Semantic proximity Read