Article

Inflammatory Triggers, Cell Death, Membrane Damage and Lipid Asymmetry That Shape Procoagulant Surfaces for Amyloidogenic Microclotting

2025-10-21

Abstract excerpt

Hypercoagulability, immunothrombosis, and protein misfolding are deeply interconnected processes that converge on cell membranes as central orchestrators of thrombo-inflammation. In health, membrane lipid asymmetry, intact glycocalyx, and regulated receptor activity maintain vascular homeostasis. During inflammation or cell death, however, phosphatidylserine (PS) externalization, protein unfolding, and damage to g...

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Literature Corpus work: 5307fd2f-23fd-5804-8835-b4232c7c3802
DOI: 10.20944/preprints202510.1460.v1

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