Article

DIA-Based Proteomics Delineates an Ordered Pathological Axis of Endothelial Barrier Disruption and Immunothrombosis in Acute Lung

2026-05-22

Abstract excerpt

<title>Abstract</title> <p>The core pathophysiological mechanism of acute lung injury (ALI) is a vicious cycle of inflammation, endothelial barrier disruption, and coagulation abnormalities. Conventional single-molecule studies cannot elucidate these mechanisms at the network-regulation level. This study combined proteomics with transcriptomic validation and identified 1,596 differentially expressed proteins in a...

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Literature Corpus work: 261cc2a8-dba5-5268-9f34-01cf4c9df883
DOI: 10.21203/rs.3.rs-9282558/v1

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DIA-Based Proteomics Delineates an Ordered Pathological Axis of Endothelial Barrier Disruption and Immunothrombosis in Acute LungDOI 10.21203/rs.3.rs-9282558/v1Read

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