Article

Cholesterol-Modified Anti-Il6 siRNA Reduces the Severity of Acute Lung Injury in Mice

2024-04-18

Abstract excerpt

Small interfering RNA (siRNA) holds significant therapeutic potential by silencing target genes through RNA interference. Current clinical applications of siRNA have been primarily limited to liver diseases, while achievements in delivery methods are expanding its applications to various organs, including the lungs. Cholesterol-conjugated siRNA emerges as a promising delivery approach due to its low toxicity and h...

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Literature Corpus work: 52cbbba1-12f9-59fd-b82c-449f51701974
DOI: 10.20944/preprints202404.1195.v1

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