Article
siRNA-Mediated Timp1 Silencing Inhibited the Inflammatory Phenotype during Acute Lung Injury.
International journal of molecular sciences - 13 Jan 2023
Chernikov Ivan V, Staroseletz Yaroslav Yu, Tatarnikova Irina S, Sen'kova Aleksandra V, Savin Innokenty A, Markov Andrey V, Logashenko Evgeniya B, Chernolovskaya Elena L, Zenkova Marina A, Vlassov Valentin V
Abstract excerpt
Acute lung injury is a complex cascade process that develops in response to various damaging factors, which can lead to acute respiratory distress syndrome. Within this study, based on bioinformatics reanalysis of available full-transcriptome data of acute lung injury induced in mice and humans by various factors, we selected a set of genes that could serve as good targets for suppressing inflammation in the lung...
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