Article

Ischemia and reperfusion-injured liver-derived exosomes elicit acute lung injury through miR-122-5p regulated alveolar macrophage polarization

2023-06-09

Abstract excerpt

<title>Abstract</title> <p><bold>Background</bold> Acute lung injury (ALI) is a common postoperative complication, particularly in pediatric patients after liver transplantation. Exosomes(Exos) are novel regulator of intercellular communications that play important roles in the pathogenesis of ALI. We previously demonstrated that hepatic ischemia-reperfusion (HIR) induces increased release of exosomes (IR-Exo) in...

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Literature Corpus work: 4b62c775-6a45-5871-9d10-e2caf4602ec5
DOI: 10.21203/rs.3.rs-3021243/v1

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