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Article

Global genetic diversity of human apolipoproteins and effects on cardiovascular disease risk.

Journal of lipid research - 1 Oct 2018

Zhou Yitian, Mägi Reedik, Milani Lili, Lauschke Volker M

Abstract excerpt

Abnormal plasma apolipoprotein levels are consistently implicated in CVD risk. Although 30% to 60% of their interindividual variability is genetic, common genetic variants explain only 10% to 20% of these differences. Rare genetic variants may be major sources of the missing heritability, yet quantitative evaluations of their contribution to phenotypic variability are lacking. Here, we analyzed whole-genome and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 30076208
DOI: 10.1194/jlr.P086710
PMCID: PMC6168301

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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