Article

CD177 is a novel IgG Fc receptor and CD177 genetic variants affect IgG-mediated function

2024-01-07

Abstract excerpt

CD177 plays an important role in the proliferation and differentiation of myeloid lineage cells including neutrophils, myelocytes, promyelocytes, megakaryocytes, and early erythroblasts in bone marrow. CD177 deficiency is a common phenotype in humans. Our previous studies revealed genetic mechanisms of human CD177 deficiency and expression variations. Up to now, immune functions of CD177 remain undefined. In the c...

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Literature Corpus work: 52a6dfd2-2266-515f-b3f9-fc9e0c8ccb57
DOI: 10.1101/2024.01.07.574546

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