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Article

CD177: A member of the Ly-6 gene superfamily involved with neutrophil proliferation and polycythemia vera

29 Mar 2004

Abstract excerpt

Genes in the Leukocyte Antigen 6 (Ly-6) superfamily encode glycosyl-phosphatidylinositol (GPI) anchored glycoproteins (gp) with conserved domains of 70 to 100 amino acids and 8 to 10 cysteine residues. Murine Ly-6 genes encode important lymphocyte and hematopoietic stem cell antigens. Recently, a new member of the human Ly-6 gene superfamily has been described, CD177. CD177 is polymorphic and has at least two...

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Share to Blood disorders and treatments
Share to Myeloproliferative Neoplasms: Diagnosis and Treatment
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PMID: 15050027
DOI: 10.1186/1479-5876-2-8

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