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Article

CD177 is a novel IgG Fc receptor and CD177 genetic variants affect IgG-mediated function.

Frontiers in immunology - 1 Jan 2024

Li Yunfang, Wu Jianming

Abstract excerpt

CD177 plays an important role in the proliferation and differentiation of myeloid lineage cells including neutrophils, myelocytes, promyelocytes, megakaryocytes, and early erythroblasts in bone marrow. CD177 deficiency is a common phenotype in humans. Our previous studies revealed genetic mechanisms of human CD177 deficiency and expression variations. Up to now, immune functions of CD177 remain undefined. In the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 39131159
DOI: 10.3389/fimmu.2024.1418539
PMCID: PMC11316256

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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