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Article

Gene silencing and a novel monoallelic expression pattern in distinct CD177 neutrophil subsets.

The Journal of experimental medicine - 3 Jul 2017

Eulenberg-Gustavus Claudia, Bähring Sylvia, Maass Philipp G, Luft Friedrich C, Kettritz Ralph

Abstract excerpt

CD177 presents antigens in allo- and autoimmune diseases on the neutrophil surface. Individuals can be either CD177-deficient or harbor distinct CD177neg and CD177pos neutrophil subsets. We studied mechanisms controlling subset-restricted CD177 expression in bimodal individuals. CD177pos, but not CD177neg neutrophils, produced CD177 protein and mRNA. Haplotype analysis indicated a unique monoallelic CD177...

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Identifiers

PMID: 28559244
DOI: 10.1084/jem.20161093
PMCID: PMC5502425

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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