Article

Total Synthesis and Bioactivity Investigation of a Chiral Diacylglycerol

2025-06-30

Abstract excerpt

<title>Abstract</title> <p>Compound <bold>1</bold>, a chiral diglyceride metabolite found in both humans and fungi, was targeted for total synthesis. A seven-step synthetic route was developed, affording compound <bold>1</bold> in 2.33% overall yield. The key steps involved: (1) selective protection of the terminal hydroxyl group of chiral ketal <bold>2</bold> with a sterically hindered benzyl group, followed by...

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Literature Corpus work: 527ac64e-1d7c-5326-9633-3f1972d599e5
DOI: 10.21203/rs.3.rs-6896088/v1

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