Article

Epigenetic signatures of chronic social stress in stress-susceptible animals

2019-07-03

Abstract excerpt

Exposure of mice to chronic social defeat stress (CSDS) produces depressive- and anxiety-like behaviors and widespread transcriptomic changes in several brain regions in susceptible animals. Here we present the first study of genome-wide cytosine methylation patterns of mice susceptible to CSDS using whole-genome bisulfite sequencing on DNA from the nucleus accumbens, a critical region for CSDS effects on behavior...

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Literature Corpus work: 524f8c0b-ae80-5f03-88c3-9fc88e4aeda1
DOI: 10.1101/690826

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