Article

Species-specific imprinting of <i>Adam23</i> and its implications for gyrencephalic brain development

2025-12-01

Abstract excerpt

Genomic imprinting is a parent-of-origin–specific epigenetic mechanism with essential roles in placental development and fetal growth in mice, but its contribution to brain function and evolution remains unclear. Here, we investigated genomic imprinting in the ferret, a gyrencephalic mammal whose cortical architecture closely resembles that of humans rather than mice. Guided by human imprinting datasets, we screen...

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Literature Corpus work: 521d59a8-2ce9-5772-b1f8-d2709ea338fa
DOI: 10.1101/2025.12.01.691626

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