Article
Convergent and divergent evolution of genomic imprinting in the marsupial Monodelphis domestica.
BMC genomics - 16 Aug 2012
Das Radhika, Anderson Nathan, Koran Maryellen I, Weidman Jennifer R, Mikkelsen Tarjei S, Kamal Michael, Murphy Susan K, Linblad-Toh Kerstin, Greally John M, Jirtle Randy L
Abstract excerpt
BACKGROUND: Genomic imprinting is an epigenetic phenomenon resulting in parent-of-origin specific monoallelic gene expression. It is postulated to have evolved in placental mammals to modulate intrauterine resource allocation to the offspring. In this study, we determined the imprint status of metatherian orthologues of eutherian imprinted genes. RESULTS: L3MBTL and HTR2A were shown to be imprinted in Monodelphis...
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