Article

Single-nuclei RNA sequencing uncovers non-cell autonomous changes in cerebellar astrocytes and oligodendrocytes that may contribute to Spinocerebellar Ataxia Type 1 (SCA1) pathogenesis

2021-10-28

Abstract excerpt

Glial cells, including astrocytes and oligodendrocytes are important for normal brain function. In many neurodegenerative diseases glial cells undergo significant morphological, functional and gene expression changes termed reactive gliosis. The cause, identity and neuroprotective or neurotoxic nature of these changes remains incompletely understood. This knowledge in needed to develop a framework of how individua...

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Literature Corpus work: 1e620019-b20e-5bfc-a24d-7a398285d6fe
DOI: 10.1101/2021.10.28.466301

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Single-nuclei RNA sequencing uncovers non-cell autonomous changes in cerebellar astrocytes and oligodendrocytes that may contribute to Spinocerebellar Ataxia Type 1 (SCA1) pathogenesisDOI 10.1101/2021.10.28.466301Read

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