Article
Proteomic and Genomic Characterization of Highly Infectious <i>Clostridium difficile</i> 630 Spores
20 Jun 2009
Abstract excerpt
Clostridium difficile, a major cause of antibiotic-associated diarrhea, produces highly resistant spores that contaminate hospital environments and facilitate efficient disease transmission. We purified C. difficile spores using a novel method and show that they exhibit significant resistance to harsh physical or chemical treatments and are also highly infectious, with <7 environmental spores per cm(2)...
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