Article

Long non-coding RNA<i>SNHG8</i>drives stress granule formation in tauopathies

2023-03-01

Abstract excerpt

Tauopathies are a heterogenous group of neurodegenerative disorders characterized by tau aggregation in the brain. In a subset of tauopathies, rare mutations in the MAPT gene, which encodes the tau protein, are sufficient to cause disease; however, the events downstream of MAPT mutations are poorly understood. Here, we investigate the role of long non-coding RNAs (lncRNAs), transcripts >200 nucleotides with low/no...

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Literature Corpus work: 516d8386-a444-527e-b923-ad7cf03e34be
DOI: 10.1101/2023.02.27.23286548

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