Article

Fast tumor phylogeny regression via tree-structured dual dynamic programming

2025-01-27

Abstract excerpt

<h4>Motivation</h4> Reconstructing the evolutionary history of tumors from bulk DNA sequencing of multiple tissue samples remains a challenging computational problem, requiring simultaneous deconvolution of the tumor tissue and inference of its evolutionary history. Recently, phylogenetic reconstruction methods have made significant progress by breaking the reconstruction problem into two parts: a regression prob...

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Literature Corpus work: 5165447d-ed5b-5711-85c5-f8e3e908bd07
DOI: 10.1101/2025.01.24.634761

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