Article

Deciphering the tissue-specific functional effect of Alzheimer risk SNPs with deep genome annotation

2024-02-08

Abstract excerpt

<title>Abstract</title> <p>Alzheimer’s disease (AD) is a highly heritable brain dementia, along with substantial failure of cognitive function. Large-scale genome-wide association studies (GWASs) have led to a significant set of SNPs associated with AD and related traits. GWAS hits usually emerge as clusters where a lead SNP with the highest significance is surrounded by other less significant neighboring SNPs. A...

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Literature Corpus work: 515f9a3e-f769-5692-b52d-3db87b658fe1
DOI: 10.21203/rs.3.rs-3871665/v1

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