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Article

Functional annotation of Alzheimer's disease associated loci revealed by GWASs.

PloS one - 1 Jan 2017

Han Zengpeng, Huang Han, Gao Yue, Huang Qingyang

Abstract excerpt

Genome-wide association studies (GWASs) discovered a number of SNPs and genes associated with Alzheimer's disease (AD). However, how these SNPs and genes influence the liability to AD is not fully understood. We deployed computational approaches to explore the function and action mechanisms of AD -related SNPs and genes identified by GWASs, including the effects of 195 GWAS lead SNPs and 338 proxy SNPs on miRNAs...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 28650998
DOI: 10.1371/journal.pone.0179677
PMCID: PMC5484478

Genes

APOE
PICALM
ABCA7
BIN1
CLU
GAB2
NME8
TOMM40
ZCWPW1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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