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Article

Genome-wide significant, replicated and functional risk variants for Alzheimer's disease.

Journal of neural transmission (Vienna, Austria : 1996) - 1 Nov 2017

Guo Xiaoyun, Qiu Wenying, Garcia-Milian Rolando, Lin Xiandong, Zhang Yong, Cao Yuping, Tan Yunlong, Wang Zhiren, Shi Jing, Wang Jijun, Liu Dengtang, Song Lisheng, Xu Yifeng, Wang Xiaoping, Liu Na, Sun Tao, Zheng Jianming, Luo Justine, Zhang Huihao, Xu Jianying, Kang Longli, Ma Chao, Wang Kesheng, Luo Xingguang

Abstract excerpt

Genome-wide association studies (GWASs) have reported numerous associations between risk variants and Alzheimer's disease (AD). However, these associations do not necessarily indicate a causal relationship. If the risk variants can be demonstrated to be biologically functional, the possibility of a causal relationship would be increased. In this article, we reviewed all of the published GWASs to extract the...

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Identifiers

PMID: 28770390
DOI: 10.1007/s00702-017-1773-0
PMCID: PMC5654670

Genes

APOE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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