Article

YAP signaling regulates the cellular uptake and therapeutic effect of nanoparticles

2023-03-10

Abstract excerpt

Interactions between living cells and nanoparticles have been extensively studied to enhance the delivery of therapeutics. Nanoparticles size, shape, stiffness and surface charge have been regarded as the main features able to control the fate of cell-nanoparticle interactions. However, the clinical translation of nanotherapies has so far been limited, and there is a need to better understand the biology of cell-n...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 5111c5a0-a16a-56ef-8af8-8bcf1220a7b2
DOI: 10.1101/2023.03.10.532035

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

YAP signaling regulates the cellular uptake and therapeutic effect of nanoparticlesDOI 10.1101/2023.03.10.532035Read

Regulation of cell–nanoparticle interactions through mechanobiologySemantic proximity Read

YAP-independent mechanotransduction drives breast cancer progressionSemantic proximity Read

Deciphering the Mechanotransduction Symphony: Stiffness-Dependent Interplay of YAP and β-Catenin in Breast Cancer MetastasisSemantic proximity Read

Magnetically Stimulated Integrin Binding Alters Cell Polarity and Affects Epithelial-Mesenchymal Plasticity in Metastatic Cancer Cells.Semantic proximity Read

YAP-mediated mechanotransduction tunes the macrophage inflammatory responseSemantic proximity Read

Micro/nano materials regulate cell morphology and intercellular communication by extracellular vesiclesSemantic proximity Read

Deciphering Cell-to-Cell Communication in Acquisition of Cancer Traits: Extracellular Membrane Vesicles Are Regulators of Tissue Biomechanics.Semantic proximity Read

Methotrexate-modulated talin-dynamics drives cellular mechanical phenotypes via YAP signalingSemantic proximity Read

Decrease in Membrane Fluidity and Traction Force Induced by Silica-Coated Magnetic NanoparticlesSemantic proximity Read

Yes-Associated Protein (YAP) Modulates Oncogenic Features and Radiation Sensitivity in Endometrial CancerSemantic proximity Read

Mechano-Sensing Channel PIEZO2 Enhances Invasive Phenotype in Triple-Negative Breast Cancer.Semantic proximity Read

Physical mechanisms of nanoparticle-membrane interactions: A coarse-grained studySemantic proximity Read