Article
Magnetically Stimulated Integrin Binding Alters Cell Polarity and Affects Epithelial-Mesenchymal Plasticity in Metastatic Cancer Cells.
ACS applied materials & interfaces - 21 Feb 2024
Kim Yu Jin, Lee Dae Beom, Jeong Eunjin, Jeon Joo Yeong, Kim Hee-Dae, Kang Heemin, Kim Young Keun
Abstract excerpt
Inorganic nanoparticles (NPs) have been widely recognized for their stability and biocompatibility, leading to their widespread use in biomedical applications. Our study introduces a novel approach that harnesses inorganic magnetic nanoparticles (MNPs) to stimulate apical-basal polarity and induce epithelial traits in cancer cells, targeting the hybrid epithelial/mesenchymal (E/M) state often linked to...
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