Article

Exercise Attenuates Obesity-Related Cognitive and Sleep-Circadian Dysfunctions by Attenuating Neuroinflammation via JAK/STAT in Sex and Age Specific Manner

2026-01-16

Abstract excerpt

<title>Abstract</title> <p> Genetic obesity is an escalating health challenge with profound consequences for brain function, yet the mechanisms linking metabolic dysfunction to disrupted brain aging remain poorly understood. Although sphingolipid dysmetabolism is strongly associated with the obesity–neuronal axis, its mechanistic basis has not been fully explored. To address this gap, our study identifies a loss...

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Literature Corpus work: 510b3234-fafb-5fec-bb0e-943db2b5267c
DOI: 10.21203/rs.3.rs-8563103/v1

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