Sedentary Life Is an Invisible Trap: Molecular, Cellular, and Systemic Reasons to Leave It Behind

Abstract excerpt

As the global population ages, the prevalence of neurodegenerative diseases has become a major public health concern. The adoption of a less sedentary lifestyle has been shown to have a beneficial effect on cognitive decline, but the molecular mechanisms responsible are less clear. Here we provide a detailed analysis of the complex molecular, cellular, and systemic mechanisms underlying age-related cognitive decli...

Topics

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• Adipose Tissue and Metabolism
• Autophagy in Disease and Therapy
• Biochemical effects in animals
• Cellular Senescence
• Diet, Healthy
• Diet, Mediterranean
• Energy Intake
• Genetics, Aging, and Longevity in Model Organisms

Identifiers and source

Literature Corpus work

b007a3f3-9edd-54d9-ba92-6f4293d8b9c8

DOI

10.20944/preprints202408.1277.v1