Article

Adipocyte sphingosine kinase 1 regulates histone modifiers to disrupt circadian function

2024-09-16

Abstract excerpt

Circadian rhythms align biological functions with the 24-hour day-night cycle, but modern artificial light disrupts these patterns, contributing to health issues like obesity and cardiovascular disease. The circadian clock operates through a transcriptional-translational feedback loop involving core components such as BMAL1 and CLOCK. Recent research has shown circadian variations in sphingolipid metabolism, speci...

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Literature Corpus work: 365541fa-b11b-5386-bf60-2f510e232294
DOI: 10.1101/2024.09.13.612486

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