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Article

The Severity of CVB3-Induced Myocarditis Can Be Improved by Blocking the Orchestration of NLRP3 and Th17 in Balb/c Mice.

Mediators of inflammation - 1 Jan 2021

Chen Jifei, Yang Fan, Shi Song, Liu Xuexiang, Qin Fengxian, Wei Xiaomou, Huang Yujie, Liang Wenwu, Miao Lin

Abstract excerpt

BACKGROUND: The functional characteristics of NLRP3 in the pathogenesis of coxsackievirus B3- (CVB3-) induced viral myocarditis (VMC) have not been fully elucidated, and the targeted therapeutic effect of NLRP3 or its related pathway in VMC has not been reported. METHOD: In this work, the change patterns of NLRP3- and Th17-related factors were detected during the pathological process of CVB3-induced VMC in Balb/c...

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Identifiers

PMID: 34093086
DOI: 10.1155/2021/5551578
PMCID: PMC8139334

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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