Article

Regulation of Liver Regeneration by hepatocyte O-GlcNAcylation in mice

2021-10-14

Abstract excerpt

The liver has a unique capacity to regenerate after injury in a highly orchestrated and regulated manner. Here we report that O-GlcNAcylation, an intracellular post-translational modification (PTM) regulated by two enzymes, O-GlcNAc transferase (OGT) and O-GlcNAcase (OGA), is a critical termination signal for liver regeneration (LR) following partial hepatectomy (PHX). We studied liver regeneration after PHX on he...

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Literature Corpus work: 50a0001a-8078-5bf0-948a-d2c22c45a979
DOI: 10.1101/2021.10.14.464401

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