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Article

FoxO3 restricts liver regeneration by suppressing the proliferation of hepatocytes

24 Jun 2022

Abstract excerpt

Abstract Upon injury, the liver is capable of substantial regeneration from the original tissue until an appropriate functional size. The underlying mechanisms controlling the liver regeneration processes are not well elucidated. Previous studies have proposed that the transcription factor FoxO3 is involved in various liver diseases, but its exact role in the regulation of liver regeneration remains largely...

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PMID: 35750775
DOI: 10.1038/s41536-022-00227-6

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