Article

Validity and Power of the Case-Only Approach in Prospective Cohort and Case-Cohort Studies with Time-to-Event Endpoints

2024-03-11

Abstract excerpt

<title>Abstract</title><p>For genetic epidemiological studies with binary outcomes, the case-only (CO) approach has been shown to be powerful for examining statistical interactions, in particular gene-environment interactions. For time-to-event outcomes, the CO approach has been extended in the context of randomized clinical trials (RCT), but has not yet been investigated in prospective observational data. We expl...

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Literature Corpus work: 5093c6bc-c5ff-5b67-8ce0-e552a4d647d0
DOI: 10.21203/rs.3.rs-3857700/v2

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