Article
Dystrophic microglia are a disease associated microglia morphology in the human brain
2020-07-30
Abstract excerpt
Microglia activation—typically described in terms of hypertrophic appearance—is a well-established feature of aging. Recent studies have suggested that microglia dystrophy, not activation, may increase the propagation of progressive neurodegenerative diseases such as Alzheimer’s disease (AD). Yet, a clear understanding of cause and consequences of dystrophic microglia is lacking. Although frequently observed in di...
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Identifiers and source
- Literature Corpus work
- 5090b8c2-0f66-581a-a27b-aedc3cc7acf8
- DOI
- 10.1101/2020.07.30.228999