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Dystrophic microglia in the aging human brain

20 Oct 2003

Abstract excerpt

We have studied microglial morphology in the human cerebral cortex of two nondemented subjects using high-resolution LN-3 immunohistochemistry. Several abnormalities in microglial cytoplasmic structure, including deramification, spheroid formation, gnarling, and fragmentation of processes, were identified. These changes were determined to be different from the morphological changes that occur during microglial...

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PMID: 14730714
DOI: 10.1002/glia.10319

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