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Article

Systems-level patterns in biological processes are changed under prolongevity interventions and across biological age

2022-07-12

Abstract excerpt

Aging manifests as progressive deterioration in cellular and systemic homeostasis, requiring systems-level perspectives to understand the gradual molecular dysregulation of underlying biological processes. Here, we report systems-level changes in the molecular regulation of biological processes under multiple lifespan-extending interventions in mice and across age in humans. In mouse cohorts, Differential Rank Con...

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Literature Corpus work
505d81f7-ce6f-5450-9823-259b69091e12
DOI
10.1101/2022.07.11.22277435
Open publication

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Systems-level patterns in biological processes are changed under prolongevity interventions and across biological ageDOI 10.1101/2022.07.11.22277435
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