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Article

Cross-species functional modules link proteostasis to human normal aging

2018-03-23

Abstract excerpt

The evolutionarily conserved nature of the few well-known anti-aging interventions that affect lifespan, such as caloric restriction, suggests that aging-related research in model organisms is directly relevant to human aging. Since human lifespan is a complex trait, a systems-level approach will contribute to a more comprehensive understanding of the underlying aging landscape. Here, we integrate evolutionary and...

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Literature Corpus work
81d0e579-b621-5614-b24b-6a4c3ed8c151
DOI
10.1101/287128
Open publication

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Cross-species functional modules link proteostasis to human normal agingDOI 10.1101/287128
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