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Article

A modular architecture of human cellular aging across organs and diseases

2026-08-13

Abstract excerpt

Aging is a heterogeneous biological process in which different cellular systems undergo molecular remodeling at distinct rates, yet whether human cellular aging follows an organized architecture across organs remains unclear. Here, we integrate a multi-organ human single-cell transcriptomic atlas with plasma proteomic profiles from approximately 50,000 participants to reconstruct cellular aging states at populatio...

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Identifiers and source

Literature Corpus work
7cc153b3-287d-538f-8add-952cf10a4e22
DOI
10.64898/2026.08.12.744367
Open publication

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A modular architecture of human cellular aging across organs and diseasesDOI 10.64898/2026.08.12.744367
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