Article

Generation of a human iPSC-derived cardiomyocyte/fibroblast engineered heart tissue model

2024-02-12

Abstract excerpt

Animal models have proven integral to broadening our understanding of complex cardiac diseases but have been hampered by significant species-dependent differences in cellular physiology. Human-induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) have shown great promise in the modelling of cardiac diseases despite limitations in functional and structural maturity. 3D stem cell-derived cardiac models re...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: b97b675c-d838-55f5-aca1-159e309f8ba7
DOI: 10.12688/f1000research.139482.2

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Generation of a human iPSC-derived cardiomyocyte/fibroblast engineered heart tissue modelDOI 10.12688/f1000research.139482.2Read

Generation of a human iPSC-derived cardiomyocyte/fibroblast engineered heart tissue modelSemantic proximity Read

Human Induced Pluripotent Stem Cells as a Disease Model System for Heart FailureSemantic proximity Read

Investigating Inherited Heart Diseases Using Human Induced Pluripotent Stem CellsSemantic proximity Read

Modeling cardiac fibroblast heterogeneity from human pluripotent stem cell-derived epicardial cellsSemantic proximity Read

Cardiac tissue engineering: Multiple approaches and potential applicationsSemantic proximity Read

Bioengineering Strategies to Create 3D Cardiac Constructs from Human Induced Pluripotent Stem CellsSemantic proximity Read

From engineered heart tissue to cardiac organoidSemantic proximity Read

Modeling Cardiovascular Diseases with hiPSC-Derived Cardiomyocytes in 2D and 3D CulturesSemantic proximity Read

Modeling cardiac fibroblast heterogeneity from human pluripotent stem cell-derived epicardial cellsSemantic proximity Read

Modeling heart disease in a dish: from somatic cells to disease-relevant cardiomyocytes.Semantic proximity Read

Human-iPSC-Derived Cardiac Stromal Cells Enhance Maturation in 3D Cardiac Microtissues and Reveal Non-cardiomyocyte Contributions to Heart DiseaseSemantic proximity Read

Human Pluripotent Stem Cell-Derived Cardiac Cells: Application in Disease Modeling, Cell Therapy, and Drug DiscoverySemantic proximity Read