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Article

Generation of a human iPSC-derived cardiomyocyte/fibroblast engineered heart tissue model

27 Sept 2023

Abstract excerpt

Animal models have proven integral to broadening our understanding of complex cardiac diseases but have been hampered by significant species-dependent differences in cellular physiology. Human-induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) have shown great promise in the modelling of cardiac diseases despite limitations in functional and structural maturity. 3D stem cell-derived cardiac models...

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PMID: 38298530
DOI: 10.12688/f1000research.139482.1

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