Article

CcBHLA: pan-specific peptide–HLA class I binding prediction via Convolutional and BiLSTM features

2023-04-28

Abstract excerpt

Human major histocompatibility complex (MHC) proteins are encoded by the human leukocyte antigen (HLA) gene complex. When exogenous peptide fragments form peptide-HLA (pHLA) complexes with HLA molecules on the outer surface of cells, they can be recognized by T cells and trigger an immune response. Therefore, determining whether an HLA molecule can bind to a given peptide can improve the efficiency of vaccine desi...

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Literature Corpus work: e0f173ef-db52-5320-b92b-984c67da3572
DOI: 10.1101/2023.04.24.538196

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