Article

Transcriptomic analyses of human brains with Alzheimer’s disease identified dysregulated epilepsy-causing genes

2025-01-02

Abstract excerpt

<h4>Background & Objective</h4> Alzheimer’s Disease (AD) patients at multiple stages of disease progression have a high prevalence of seizures. However, whether AD and epilepsy share pathophysiological changes remains poorly defined. In this study, we leveraged high-throughput transcriptomic data from sporadic AD cases at different stages of cognitive impairment across multiple independent cohorts and brain region...

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Literature Corpus work: c2d7a019-4445-5d4c-b823-e86e6b2fca0b
DOI: 10.1101/2025.01.02.25319900

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