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Article

Transcriptional Alterations Related to Neuropathology and Clinical Manifestation of Alzheimer’s Disease

7 Nov 2012

Abstract excerpt

Alzheimer's disease (AD) is the most common cause of dementia in the human population, characterized by a spectrum of neuropathological abnormalities that results in memory impairment and loss of other cognitive processes as well as the presence of non-cognitive symptoms. Transcriptomic analyses provide an important approach to elucidating the pathogenesis of complex diseases like AD, helping to figure out both...

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PMID: 23144955
DOI: 10.1371/journal.pone.0048751

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