Article

Mitotic events depend on regulation of PLK-1 levels by the mitochondrial protein SPD-3

2023-01-12

Abstract excerpt

In metazoans, Polo Kinase (Plk1) controls several mitotic events including nuclear envelope breakdown, centrosome maturation and kinetochore assembly. Here we show that mitotic events regulated by Polo Like Kinase (PLK-1) in early C. elegans embryos depend on the mitochondrial-localized protein SPD-3. spd-3 mutant one-cell embryos contain abnormally positioned mitotic chromosomes and prematurely and asymmetrical...

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Literature Corpus work: 4f6f35c8-bbf7-58fa-8408-d665fc374aef
DOI: 10.1101/2023.01.11.523633

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