Article

Robust diagnosis of infectious disease, autoimmunity and cancer from the paratope networks of adaptive immune receptors

2023-11-30

Abstract excerpt

Liquid biopsies based on peripheral blood offer a minimally invasive alternative to solid tissue biopsies for the detection of diseases, primarily cancers. However, such tests currently consider only the serum component of blood, overlooking a potentially rich source of biomarkers: adaptive immune receptors (AIRs) expressed on circulating B and T cells. Machine learning-based classifiers trained on AIRs have been...

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Literature Corpus work: 4f169d64-93e4-5433-8bca-8becbf9ec2c0
DOI: 10.1101/2023.11.28.569125

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