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Article

Immunosignature system for diagnosis of cancer

14 Jul 2014

Abstract excerpt

Although the search for disease biomarkers continues, the clinical return has thus far been disappointing. The complexity of the body's response to disease makes it difficult to represent this response with only a few biomarkers, particularly when many are present at low levels. An alternative to the typical reductionist biomarker paradigm is an assay we call an "immunosignature." This approach leverages the...

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PMID: 25024171
DOI: 10.1073/pnas.1409432111

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