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Single Cell RNA-sequencing of BCG naïve and recurrent non-muscle invasive bladder cancer reveals a CD6/ALCAM-mediated immune-suppressive pathway

2025-02-17

Abstract excerpt

<h4>ABSTRACT</h4> Non-muscle invasive bladder cancer (NMIBC) represents 70–80% patients with newly diagnosed bladder cancer, and Bacillus Calmette-Guérin (BCG) remains a cornerstone treatment for intermediate-and high-risk NMIBC to prevent disease recurrence and progression. However, many patients experience recurrence after induction BCG, posing significant challenges in the management of the disease. We conduct...

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Literature Corpus work
4f14acea-d71a-50cc-bcb6-2cb76c337d12
DOI
10.1101/2025.02.13.638074
Open publication

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Single Cell RNA-sequencing of BCG naïve and recurrent non-muscle invasive bladder cancer reveals a CD6/ALCAM-mediated immune-suppressive pathwayDOI 10.1101/2025.02.13.638074
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