Article
The impact of single-nucleotide polymorphisms on intravesical recurrence after bacillus Calmette-Guérin therapy for non-muscle invasive bladder cancer in a genome-wide association study.
Urologic oncology - 1 Oct 2021
Nagakawa Shohei, Shiota Masaki, Fujimoto Naohiro, Yamamoto Yoshiaki, Blas Leandro, Tsukahara Shigehiro, Matsumoto Takashi, Kashiwagi Eiji, Takeuchi Ario, Inokuchi Junichi, Uchiumi Takeshi, Matsuyama Hideyasu, Eto Masatoshi
Abstract excerpt
OBJECTIVE: Bacillus Calmette-Guérin (BCG) instillation therapy is widely used to reduce intravesical recurrence in non-muscle invasive bladder cancer (NMIBC). In this study, we aimed to reveal the genetic variations associated with intravesical recurrence after BCG therapy for NMIBC in a genome-wide association study (GWAS). MATERIALS AND METHODS: This study included Japanese patients with NMIBC, in whom genomic...
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